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According to FDA prescribing information, fatigue occurs in approximately 11% of patients taking Wegovy and 5-9% of patients taking Saxenda

Second, lack of durable exposure or poor temporal alignment between dosing and physiology suggests pharmacologic failure

Abstract Despite the strong immune-modulatory benefits, there has been a lag in using glucagon-like peptide-1 receptor agonists (GLP-1RAs) in rheumatoid arthritis (RA) due to inefficient articular delivery and poorly understood direct cartilage protection

Both formulations being developed in parallel

Lets hope that both RECOVER and Scripps groups have chosen well