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Although VSG does not induce intestinal hypertrophy like RYGB 21 , intestinal stem cell differentiation is shifted away from absorptive cells and towards secretory cell lineages in mice 26

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Although findings in human studies have been less consistent, a pilot study reported reduced cerebrospinal fluid levels of A42, and a large-scale clinical trial is currently underway to assess the efficacy of a GLP-1RA in early-stage AD patients ( These pharmacological advances have reshaped the management of metabolic diseases, improving glycemic control, weight reduction, and cardiovascular outcomes

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Tightening the core to improve posture and stability