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Brain Sci 14:617 Badulescu S, Tabassum A, Le GH et al (2024) Glucagon-like peptide 1 agonist and effects on reward behaviour: a systematic review

The treatment-regimen estimand results at 68 weeks showed -20.0% body weight change (approximately 50.5 pounds) in the 9 mg group and -23.7% (approximately 60 pounds) in the 12 mg group

It improved glucose homeostasis in diet-induced obesity, ob/ob, and db/db mice, with more substantial antidiabetic effects than celastrol, a highly potent leptin sensitizer, in ob/ob and db/db mice (94)

The glucagon-like peptide 1 analogue Exendin-4 attenuates alcohol mediated behaviors in rodents

have a Cooperative Research and Development Agreement to develop exendin-4 (exenatide) as a treatment strategy for neurodegenerative disorders for which NIA and Peptron Inc