glp 1 reduces inflammation GLP-1 and Gut Health: Addressing Metabolic Dysfunction for Physicians GLP-1 RAs may lead to

However, Mounjaro is a completely different medication from Foundayo (orforglipron)different molecule, different mechanism (dual GIP/GLP-1 vs GLP-1 only), and different administration (injection vs pill)

This is particularly due to its association in the increased incidence of endometrial lesions (including hyperplasia, carcinomas, and sarcoma) found in women undergoing chronic treatment with tamoxifen

This discouraged researchers from pursuing GIP as a therapeutic target

Severe caloric restriction, which can happen when appetite suppression is intense, may impair gland function beyond what the medication itself causes

The drugs initially were developed to treat diabetes, before their weight loss benefits were observed