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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have become essential medications in the management of type 2 diabetes mellitus and obesity due to their ability to improve glucose control and facilitate weight loss by enhancing insulin ...

GLP-1 receptor (GLP-1R) agonists, like liraglutide, have shown analgesic effects by modulating pain hypersensitivity in animal models of inflammatory and neuropathic pain

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A review by Frank Duca and graduate students Hallie Wachsmuth and Savanna Weninger at the University of Arizona, Tucson, USA, reveals a more complicated picture, with many different interacting neural and hormonal signals, with increasing evidence for the vital role played by the microbes in the gastrointestinal tract

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