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That is the entire mechanism

Patients with the following characteristics often see the strongest improvements: Rheumatoid arthritis Psoriatic arthritis Osteoarthritis of the knees or hips Obesity or insulin resistance Chronic fatigue Long-term steroid use Difficulty losing weight despite trying Who Should Avoid GLP-1

If below 1.2 grams per kilogram body weight, this is almost certainly a major contributor to your fatigue

GLP-1 RAs provide the most potent and sustained appetite suppression, making them highly sought after by patients

In this review I aim to re-examine the contested concept of food addiction as a disease in the context of emerging GLP-1based obesity pharmacotherapies, integrating perspectives from neurobiology, societal impacts, and early evidence for their potential application in other substance-use disorders