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Intestinal and brain cells contain prohormone convertase 1 (PC1), which is able to cleave proglucagon into Glicentin, Oxyntomodulin, GLP-1, GLP-2 and IP-2, while pancreatic islet cells contain prohormone convertase 2 (PC2), which capable of cleaving proglucagon into Glucagon and MPGF

Here, weve compiled tips from experts about what to eat, how to eat and how to exercise to minimize the side effects of taking a GLP-1 medication: 1
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If you're also taking insulin or sulfonylureas and experiencing hunger or hypoglycaemia symptoms, these medications may need dose adjustment

When GLP-1 signaling increases, this can help push the brain toward a state where appetite is reduced
