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This is particularly important with tirzepatide, which can reduce oral contraceptive exposure during initiation and dose escalation, potentially requiring backup contraception

GLP-1 is able to stimulate cAMP formation in RIN 1046-38 cells, which in turn causes an increase in insulin mRNA levels and insulin release, and insulin accumulation in the culture fluid was observed by adding GLP-1 (7-37) to RIN 1046-38 cells for 1 h incubation (Drucker et al., 1987)

McCarty, D., Coleman, M

The Source: This article includes information from CVS Caremark, The Associated Press and previous FOX Local reporting.

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