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The results demonstrated that subcutaneous tirzepatide was the most cost-effective option for adults with obesity without diabetes, being cost-effective at a WTP threshold of $150,000 per QALY gained compared with oral semaglutide and dominating over both subcutaneous liraglutide and subcutaneous semaglutide over a 68-week time window

This hormone is responsible for regulating appetite and insulin secretion

In fact, the GLP-1 RAs can be categorised structurally into two major groups (see Table 1

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