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[3] [4] The delayed gastric emptying effect varies in intensity among different agents and individual patients, with clinical implications that warrant careful consideration in practice

Common Side Effects: Nausea : This is the most common side effect and usually occurs when starting the medication or after increasing the dose

Semaglutide may also upregulate transcriptional responses to oxidative stress, which decrease with ageing, owing to the declining function of the stress-responsive NRF2 [194]

However, it is noteworthy that a 26-week treatment of dulaglutide 1.5 mg or tirzepatide 5 mg showed comparable outcomes in improvements of MASH and liver fibrosis biomarkers, including liver enzymes, keratin-18, procollagen III, and adiponectin