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However, caution should be used when interpreting these data because the grading system used to evaluate CRS in these trialsthe National Cancer Institute Common Terminology Criteria for Adverse Eventshas been shown to be inconsistently applied by investigators [133]

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If this patient continues to take doses of size 5 mg, then the blue dashed curve shows how the efficacy decreases as the cost decreases by decreasing the dose frequency

Computed tomography (CT) abdomen and pelvis revealed moderate intrahepatic biliary dilatation and suspected cholangitis, multifocal hepatic hypodensities, an indeterminate lesion in the left kidney, and severe sigmoid diverticulosis with incomplete large bowel obstruction