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Despite these encouraging findings, further research is still needed to understand more thoroughly the mechanisms by which GLP-1RAs may mediate stroke protection specifically in the human diabetic brain.
Conclusions GLP-1RAs had a neutral effect on the composite cardiovascular outcomes but reduced composite kidney events in the patients with advanced DKD compared with DPP-4is.
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The Novo Nordisk-funded FLOW trial, published in the New England Journal of Medicine on 24 May 2024, randomly assigned patients with T2DM and []
