are glp-1 agonists safe A Comprehensive Review of the Role of in Weight Management and Their Effect on Metabolic Parameters Such as Blood Glucose, Cholesterol, and Blood Pressure GLP-1 Receptor Agonists as Treatments
Description
So the most fair interpretation is not, Berberine is useless. The fair interpretation is: Berberine may produce modest metabolic effects, but its weight-loss effect is nowhere near the effect seen with GLP-1-based obesity medications

PLoS One 7: e40156

After success with weight loss GLP-1 drugs, IBX patients face high costs after insurer drops coverage for obesity Independence Blue Cross began limiting coverage of GLP-1 drugs on Jan
Sustaining the healthcare system requires meticulous evaluation of budgetary implications

When you start taking GLP-1s, there are many new changes to navigate