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Holding GLP-1RAs before endoscopy may disrupt diabetes management and increase procedure cancellations, yet our findings suggest this practice is justified by the increased, albeit modest, risk of aspiration, especially in upper GI and propofol-assisted procedures, Yeo and colleagues wrote

I do not think we have complete answers to these questions yet, and I want to be honest about that uncertainty with my patients rather than offering false reassurance in either direction

Regardless of the limitations, this study provides additional support for maintaining NPO status for solids for more than 24 hours and suggests that holding GLP-1 receptor agonists for even one half-life may be beneficial

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