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A recent genetic study has provided new insights into how glucagon-like peptide-1 (GLP-1) receptor agonists aid weight loss

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A sensitized high-throughput screen identified a series of small molecule GLP-1R agonists that were optimized to promote endogenous GLP-1R signaling with nM potency

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Gastric emptying (acetaminophen absorption method), glycemic parameters and appetite were assessed during a 5-h meal test