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Description
The beneficial effects of GLP-1 result from the cAMP-activated PKA signaling in the activation of pro-survival cAMP-responsive element binding (CREB) which, upon phosphorylation at Ser133, promotes its interaction with target genes containing palindromic CRE repeat sequences, including the same insulin gene [21]
doi:10.1177/10600280251407145
Dendritic cells (DCs) DCs serve a pivotal role in initiating and regulating T cell-mediated antitumor immune responses by enhancing the cytotoxicity of NK and T cells (137)
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