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It triggers the release of insulin, which helps to regulate blood sugar levels, slow digestion and increase feelings of fullness.[1][2] These effects are why GLP-1-based medications (such as Mounjaro and Ozempic) have become so widely used in the management of type 2 diabetes and weight loss

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376,377,378 In a dexamethasone-induced muscle atrophy model, Ex-4 ameliorated muscle atrophy by inhibiting muscle atrophy factor and enhancing myogenic factors (MyoG and MyoD), thereby increasing muscle mass and function

Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations

GLP-1 is both anxiogenic and antidepressant