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Basal doses declined by about 10 units, bolus insulin by about 15 units

For example, the FDA has approved the following drugs when combined with diet and exercise: Wegovy and Zepbound (trade names) to reduce excess body weight and maintain weight reduction long term in adults with obesity or adults who are overweight and have at least one weight-related condition

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Conclusions This meta-analysis highlights the substantial and multidimensional clinical benefits of GLP-1 RAs therapy in individuals with overweight or obesity, with or without T2DM

doi: 10.1161/01.cir.91.10.2516