![glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://medrac.web.unc.edu/wp-content/uploads/sites/22579/2025/03/image-6.png)
glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]
Description
In terms of side effects and tolerability, the advantage goes to neither (comparable)
![glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://tmedweb.tulane.edu/pharmwiki/lib/exe/fetch.php/glp1_cellular_moa.png)
T., Geerling J
![glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.nejm.org/cms/10.1056/NEJMcibr2409089/asset/1f854e14-bfd6-40e1-8b1c-03461c2a1ab4/assets/images/large/nejmcibr2409089_f1.jpg)
You can visit a doctor on your smartphone or computer
![glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://cdn2.caymanchem.com/cdn/cms/caymanchem/PublishingImages/Lists/NewsItems/AllItems/Summary%20of%20insulin%20and%20glucagon%20pathways%20in%20glucose%20homeostasis.png)
While these earlier drugs demonstrated the potential of GLP-1 therapy, the newer medications semaglutide, tirzepatide, and retatrutide have completely changed the game
![glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.frontiersin.org/api/ipx/w=1200&f=png/https://www.frontiersin.org/files/Articles/1431292/fendo-15-1431292-HTML-r1/image_m/fendo-15-1431292-g001.jpg)
[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Ali S., Drucker D.J
![glp-1 moa Receptor Agonists as Treatments for Type 2 Diabetes glp-1_ra_pharmacology [TUSOM | Pharmwiki]](https://www.researchgate.net/publication/371461642/figure/fig2/AS:11431281210340311@1702043944953/Mechanisms-of-action-of-GLP-1RA.jpg)
