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A 2024 pooled analysis of the SURMOUNT trials (Aronne et al., Lancet ) found that 4.3% of patients discontinued tirzepatide due to GI side effects

-The EMA states: up to 1 in 10,000 people taking semaglutide may be affected by NAION. -The WHO also issued a safety alert referencing this risk

Many individuals with Hashimoto's thyroiditis also have type 2 diabetes or obesity, conditions for which GLP-1 medications are indicated
