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What This Looks Like in Practice If you're on Ozempic, Wegovy, or any GLP-1 medication, here's what an effective training approach includes: Frequency: 23 strength sessions per week minimum Focus: Compound movements squats, deadlifts, pressing, pulling that recruit the most muscle Protein: Aim for 1.62.2g per kg of bodyweight daily to offset appetite suppression Intensity: Keep training challenging appetite suppression can reduce perceived effort, but the muscle stimulus still needs to be there Recovery: Prioritise sleep and manage stress, both of which affect muscle retention Training on GLP-1 in Singapore: What to Expect Lower appetite can affect energy levels, especially in the first 48 weeks of GLP-1 use

GLP-1 Receptor Activation Suppresses appetite and slows gastric emptying Improves insulin sensitivity Reduces fat storage 2

MHRA-approved product information (SmPCs and PILs) confirms that the abdomen, thigh or upper arm are acceptable sites for subcutaneous GLP-1 injections

These three key parameters showed no significant differences between the 4-week and 8-week PAB groups (Supplementary Figure S2)
