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Introduction Recent pharmaceutical developments with Glucagon-like Peptide-1 Receptor Agonist (GLP-1RA), such as incretin-based and glucagon-like peptide-1 receptor agonists, have significantly advanced medical treatments for obesity [1]

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The suggested treatment algorithm of the ADA and EASD stratifies patients without pre-existing cardiovascular disease further

Accordingly, a significant increase in glucagon levels could compete with [ 68 Ga]Ga-DO3A-Tuna-2 for the GCGR, presented as an apparent decrease in [ 68 Ga]Ga-DO3A-Tuna-2 binding