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SURMOUNT-1 enrolled 2,539 adults with obesity or overweight

Systolic blood pressure decreased significantly across all doses, with reductions ranging from 5-8 mmHg depending on dose and duration

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When that fat disappears quickly, the skin sags and wrinkles become more visible

GLP 1RAs treatment, source: reference [1] Semaglutide Reduces Cardiovascular Disease Risk As obesity is an important risk factor for cardiovascular disease, weight loss should theoretically reduce the risk of cardiovascular disease in participants, however, this speculation has not been validated by clinical trials
