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The complaints women are reporting: Pain when biking or sitting on hard surfaces Vaginal dryness Weaker pelvic floor muscles Changes in how underwear feels Increased discharge as lubricated tissue tries to compensate One woman lost 44 pounds, no sagging on arms or stomach

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Diabetes1996 Jun;45(6):832-5
Garrison SR, Dormuth CR, Morrow RL, Carney GA, Khan KM

Semaglutide is contraindicated at all doses during pregnancy because animal studies have shown fetal developmental concerns and there are no human safety trials