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LEADER [29] and SUSTAIN-6 [30] reported a prespecified renal composite of new onset or persistent macroalbuminuria, persistent doubling of serum creatinine and eGFR 45 mL/min/1.73 m 2 , need for renal replacement therapy (RRT), and renal death

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Several other case reports have documented potential drug interactions between cannabinoids and oral anticoagulants [79]

Diabetic Nephropathy: Kidney damage caused by high blood sugar levels over time, leading to reduced kidney function and potentially kidney failure

Patients were randomized in a 5:1:1 ratio to either WEGOVY 7.2 mg, WEGOVY 2.4 mg or placebo once weekly