can you fast while on glp 1 Fasting a GLP-1 is not a simple yes or no., The medication is already suppressing your appetite and regulating hunger. Adding aggressive fasting on top of that put your protein intake, Can You Take GLP-1 Medications

Also, as I wrote about recently, these drugs can have pretty dramatic effects beyond their ability to curb appetite for food decreasing compulsive gambling and shopping, reducing alcohol intake, and helping to quit smoking

Combination therapy is not recommended both medications should not be taken together as it can be unsafe and may increase gastrointestinal side effects

Metformin: Co-administration of multiple twice-daily doses of sitagliptin with metformin, an OCT substrate, did not meaningfully alter the pharmacokinetics of metformin in patients with type 2 diabetes

doi: 10.1212/WNL.56.3.375 [DOI] [PubMed] [Google Scholar] 22.Kostic V, Przedborski S, Flaster E, Sternic N

Sodium-glucose cotransporter-2 inhibitors: understanding the mechanisms for therapeutic promise and persisting risks