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Long-term arrhythmia can weaken the heart muscle

Semaglutide and Heart Attack Risk: What Clinical Evidence Shows The SUSTAIN-6 trial, which tracked over 3,000 patients for three years, demonstrated that semaglutide reduced major adverse cardiovascular events by 26% compared to placebo

While thats not the healthiest way to handle those few extra pounds, its certainly not as newsworthy as taking semaglutide

4 Clinical evidence In adults with obesity, 72 weeks of orforglipron treatment resulted in greater body-weight reductions than placebo, up to -11.2%, compared to -2.1% with placebo

This article covers what the GLP-1 class actually does to digestion across the major drugs in this category, what published evidence shows for probiotics on bloating and related gut discomfort, and how to evaluate options realistically