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This is consistent with other GLP-1 and GIP agonists, which do not adjust dosing based on sex

[Google Scholar] 7.Gleason P.P., Urick B.Y., Marshall L.Z., Friedlander N., Qiu Y., Leslie R.S

Yes, for optimal results, it is generally recommended to combine GLP-1 therapy with lifestyle changes, such as a healthy diet and regular physical activity

Incretin-based antidiabetic therapies, such as glucagon-like peptide-1 receptor agonists (GLP-1RAs), may offer benefits for individuals at risk of neurodegeneration due to their central effects on appetite and satiety regulation via the hypothalamus (Correia et al., 2012)

Low dose glucagon agonism may therefore enhance insulin sensitivity which is in keeping with pre-prandial physiology in the fasted setting where the body is prepared to metabolise essential nutrients
