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Indeed, early preclinical studies demonstrated attenuation of renal TGF- expression in association with reduced expression of collagens within the kidney after GLP-1 receptor agonist therapy (62)

[DOI] [PubMed] [Google Scholar] 139.Korovila I., Hugo M., Castro J.P., Weber D., Hhn A., Grune T., Jung T

Lancet 2021, 398, 21602172
Worsening diabetic retinopathy: Rapid improvement in blood sugar can temporarily worsen eye damage in diabetic patients

SnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and hyperphagia in mice