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Both TNF- and IL-6 can reduce the expression of intracellular glucose transporter 4 (GLUT4), inhibit normal phosphorylation of insulin receptors and insulin receptor substrate 1 (IRS-1), block GLUT4 translocation, and lead to IR

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2009), while other AAV serotypes have been used for targeting other cell populations in the CNS, such as astrocytes (Hanlon et al

2013;36(10):e171-e172
