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The most intriguing development is the emergence of biased agonists
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Prior to initiation of treatments, mice were randomized and distributed into groups allowing similar mean values of body weight and fat mass
The ophthalmic drugs in development, and the new solutions that they require, have created a steady stream of device innovation over recent years that is expected to continue, or even increase, in 2024
Until those data arrive, claims about meaningful, reproducible benefits should be treated as hypotheses
