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Semaglutide use is increasingly associated with gastroparesis, a condition marked by delayed gastric emptying, causing nausea, vomiting, abdominal pain, bloating, satiety, acid reflux, and blood sugar fluctuations
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Small interfering RNA (siRNA) GLP-1R expression in chondrocytes was silenced by transfection of siRNA
GLP-1 agonists should be initially prescribed at the lowest dose and slowly uptitrated to avoid gastrointestinal side effects
