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NIT-1 cells treated with PA+Ex-4 and PA+GW showed enhanced GSIS capacity, increased PPAR expression, decreased UCP2 expression and ADP/ATP ratio, and improved mitochondrial DNA content and mitochondrial membrane potential compared with those treated with PA alone, whereas the opposite results were observed in the PA+GSK group

Access this presentation on ESC 365 from ESC Congress 2025 on Antidiabetic Pharmacotherapy by Professor R
Semaglutide triggers nausea and stomach discomfort in up to 40% of patients during the first month

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