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These are signs that the glucagon component is driving energy expenditure at a level that meaningfully contributes to the overall weight loss beyond what GLP-1 and GIP provide alone

Changes in leptin signaling by SOCS3 modulate fasting-induced hyperphagia and weight regain in mice

2001;12(2 Suppl):S6368

He has received unrestricted research grants from Celgene/BMS and Novartis
GLP-1 also has cardio- and neuroprotective effects, decreases inflammation and apoptosis, and has implications for learning and memory, reward behavior, and palatability
