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Effective contraception is advised for women of childbearing potential while using this medication

Altered CAMKII expression, which regulates orexigenic neuropeptides like NPY, also reflected compensatory adaptation to weight loss ( Previous studies in obese rodents and diet-induced obesity models have shown that GEs primary site of action is central, particularly within hypothalamic regions such as the supramammillary nucleus, lateral hypothalamus, and the nucleus of the solitary tract ( Proteomic analyses of the hypothalamus following GE treatment revealed downregulation of inflammation-, apoptosis-, and immune-related proteins, and upregulation of pathways related to autophagy, vesicular transport, and intracellular signaling

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Capehorn, M

She said for Houstonians considering or already taking these medications, the findings may offer additional reassurance