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Future directions The reduction of inflammation is of fundamental importance in HFpEF treatment, as CRP was associated both with cardiovascular mortality and all-cause mortality in a recent meta-analysis [56]

Finally, it helps the pancreas release the right amount of insulin when blood sugar levels are high, which helps the body process energy more efficiently

For example, a recent meta-analysis of two randomized controlled trials showed that SGLT2i significantly reduced N-terminal B-type ANP (NT-proBNP) levels compared with placebo [57, 58], although Ueda et al

This is a normal and expected response to weight loss, not a side effect of the medication itself

As women move through perimenopause and beyond, hormonal shifts already influence muscle mass, sleep quality, metabolic resilience, and recovery