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Description
We report herein a series of pharmacological and molecular studies in two validated mouse models of PCOS, generated by gestational (PNA) or postweaning (PWA) androgenization, addressing the effects of GLP1-based multi-agonist therapies on metabolic and reproductive traits of PCOS
In comparing GLP-1RAs with these medications, no significant difference in intestinal obstruction risk was observed
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Its role exhibits context-dependent duality, functioning as a cytoprotective mechanism or contributing to regulated cell death (Levine and Kroemer, 2019)
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