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GLP-1 receptors (e.g., liraglutide and semaglutide) act through GLP-1 receptors activating intracellular signaling pathways (cAMP/PKA/CREB, PI3K/AKT, and MAPK/ERK) which regulate metabolic, proliferative, and differentiation processes

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eine bevorzugte glukosesenkende Therapie fr Patienten mit einem Diabetes mellitus Typ 2 (T2DM) und atherosklerotischen Herz-Kreislauf-Erkrankung (ASCVD), unabhngig von berlegungen zur Glukosekontrolle und unabhngig von der Hintergrundanwendung von Metformin