when you stop taking tirzepatide what happens Stopping GLP-1s: Weight Regain and Maintenance Tips What to Expect After Starting

While absolute lean mass decreased with weight loss, the percentage of body weight comprised by lean tissue actually increased in tirzepatide-treated patients, suggesting preferential fat loss

While Semaglutide and Tirzepatide are not muscle-building drugs, they create an environment where building lean muscle is possible with adequate protein and resistance training

Clinical studies show that people using tirzepatide can lose a significant amount of weight over time, often averaging 15% to 22% of their body weight after about a year, depending on the dose and individual factors

References Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al

Some researchers find that they can reduce their dose to 1.7 mg after reaching their target and maintain results, though this should be discussed with a healthcare provider