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It became relatively quickly clear we need to combine several signals. Fast forward to 2003

One-year sustained glycemic control and weight reduction in type 2 diabetes after addition of liraglutide to metformin followed by insulin detemir according to HbA1c target

Patients treated with GLP-1 therapies often lose significant weight and improve overall metabolic health

In this randomized clinical trial, scientists have investigated whether a combination of a 5:2 intermittent fasting diet and a meal replacement diet can effectively control blood glucose levels and reduce body weight in obese or overweight Chinese adults with early type 2 diabetes

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