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In the ACHIEVE-1 phase 3 trial, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with early type 2 diabetes

On 21 May 2026, Eli Lilly published the topline TRIUMPH-1 Phase 3 results everyone in the metabolic-health space was waiting for

data analytics at Clarivate, said.

That might show up as a great result on the scale, but it leaves people metabolically weaker, not stronger

Lemas, PhD, assistant professor in the department of health outcomes and biomedical informatics, and faculty member at the Institute for Child Health Policy at