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9 While SEM at higher doses than 1.0 mg are being used in Canada, there is also the potential for increased cost and risks associated with the higher, 2.0 mg once-weekly dose without a comprehensive evidence review for its benefits

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This is why regular follow-up care and blood work are essential when starting any new medication

Mechanisms of Toxicity Image 2 (Source) The mechanism of toxicity for each aforementioned venom component will be described individually below

DPP-4 is present on the apical endothelial surface of capillaries including those in the intestine