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This can lead to weight loss by decreasing insulin resistance and helping to regulate appetite

The average BMI decreased from 43.1 to 41.5, while the average weight dropped from 117.7 kg to 111.6 kg, with one-third of participants losing 10 kg or more during the treatment period

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Certain effects, like appetite suppression, can still occur at low doses, while others, like substantial weight loss or blood sugar changes, require higher dosing, she says
