stopping glp 1 before surgery What Happens When You Stop GLP-1s — And How to Prevent Weight Regain Study Challenges Seven-Day Hold on

10.1007/s00702-024-02792-0 62 JiangY.WangZ.MaB.FanL.YiN.LuB.et al (2018)

The UVA team found that, in addition to those established effects, the drugs also engage a separate circuit linking the hindbrain to the central amygdala, which is involved in processing emotions, and ultimately to dopamine-producing neurons

Nausea reduces fluid intake because people simply do not feel like drinking when they feel sick

Meaning they dont lose meaningful weight at all

GLP-1 is also produced in the central nervous system of humans, predominantly in the brainstem neuronal cells of the nucleus tractus solitarius of the central nervous system, to be distributed to other central nervous areas, such as the hypothalamus thalamic and cortical areas