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Furthermore, a GLP-2 analogue with a single amino acid substitution [Gly2]-GLP-2 exhibited substantial resistance to DPP-4 cleavage and robust intestinotrophic activity in normal rats in vivo (60)
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The reason that GLP-1-based medicines including retatrutide, semaglutide, and liraglutide are predominantly delivered by injection relates directly to their chemical structure
[DOI] [PubMed] [Google Scholar] 228.Buse JB, Drucker DJ, Taylor KL, et al
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