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To minimize selection bias, we employed 1:1 propensity score matching to account for demographic factors such as age, sex, race, and comorbidities

These results highlight significant heterogeneity in weight trajectories following sustained exposure to a GLP-1RA therapy and identifies factors associated with increased weight loss, likely reflecting a combination of biological, behavioral, and social factors

The research reviewed data from 120 participants with overweight or obesity who received tirzepatide, marketed in the UK at Mounjaro, for weight management for 12 or more months

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PlexusDx explains the mechanism, who's at higher risk, and practical management strategies for GLP-1 users