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The amount of water you add determines the concentration, which directly affects your dosing accuracy

[DOI] [PubMed] [Google Scholar] 14.Cipriani A, Higgins JPT, Geddes JR, Salanti G

In addition, the treatment response observed in our analysis may also be influenced by ethnic differences, given that five RCTs recruited exclusively Japanese participants [3941, 48, 49]

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Sitagliptin, a dipeptidyl peptidase-4 inhibitor, was selected as an active-comparator placebo proxy because it was recommended in clinical guidelines as a second-line glucose-lowering therapy, had a similar high cost to the study drugs, showed no effect on cardiovascular outcomes in a large randomized controlled trial and has been validated as a placebo proxy in prior claims-based research 20,41