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The prevalence of HFpEF is rising, increasing from 33 to 39% between 2005 and 2010, with projections suggesting it will soon become the most common form of HF [5, 6]

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However, clinical studies have shown that many patients on semaglutide GLP-1 experience a significant weight reduction, with some patients reporting a loss of about 5-10% of their initial body weight in the first month of treatment