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Closest Analog: Cagrilintide + Semaglutide REDEFINE 1 (Garvey et al., NEJM 2025) is the only Phase 3 trial of an amylin + incretin co-administered combination in adults without diabetes

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Peptide Sciences, one of the most established and compliance-minded vendors in the grey-market research peptide space, voluntarily shut down in March 2026 under this same pressure, having first removed all GLP-1 peptides from its catalog in an attempt to remain operational before concluding the risk was too great