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Medium-chain fatty acids such as sodium caprate (C10) were among the most extensively studied, demonstrating the ability to open tight junctions and enhance paracellular transport

Recent studies show that this class of drugs is effective in lowering risk of cardiovascular disease and improving sleep apnea and might be appropriate to treat fatty liver disease, Alzheimers disease, smoking cessation and substance use disorder

Our study included any GLP-1 receptor agonists that were prescribed during the study period in Ontario, Canada

Weight loss may plateau, blood glucose targets remain out of reach, or side effects limit long-term use

In addition, we included semaglutide prescriptions where the brand was unknown, if the patient had prior evidence of obesity and no prior evidence of type 2 diabetes (T2D)